MICB Antibody (102) [Janelia Fluor® 585]

Product Discontinued

MICB Antibody (102) [Janelia Fluor® 585] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Human MICB (Accession#: NP_005922.2; Met1-Gly298).
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: MICB
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for MICB Antibody (102) [Janelia Fluor® 585]

• MHC class I chain-related protein B
• MHC class I mic-B antigen
• MHC class I polypeptide-related sequence B
• MICB
• MIC-B
• PERB11.2MHC class I-like molecule PERB11.2-IMX
• stress inducible class I homolog

Background

MICB encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MICB