Meteorin-like/METRNL Antibody (781718R) [Unconjugated]

Recombinant Human Meteorin‑like/METRNL protein was serially diluted 2-fold and captured by Mouse Anti-Human Meteorin‑like/METRNL Monoclonal Antibody (Catalog # MAB7867) coated on a Clear Polystyrene Microplate (Catalog # DY990). Mouse Anti-Human Meteorin‑like/METRNL Monoclonal Antibody (Catalog # MAB78671) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998) followed by Substrate Solution (Catalog # DY999) and stopping the enzymatic reaction with Stop Solution (Catalog # DY994).

• Reactivity: Hu
• Applications: ELISA
• Clone: 781718R
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

Meteorin-like/METRNL Antibody (781718R) [Unconjugated] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human Meteorin‑like/METRNL
  Gln46-Asp311
  Accession # Q641Q3
• Specificity: Detects human Meteorin‑like/METRNL in direct ELISAs.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified from cell culture supernatant

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Meteorin-like/METRNL Antibody (781718R) [Unconjugated]

• Meteorin like
• meteorin, glial cell differentiation regulator-like
• meteorin-like protein
• Meteorin-like
• METRNL
• MGC99788

Background

METRNL (Meteorin-like) is a cytoplasmic 30 kDa (predicted) member of the meteorin family of proteins. The name meteorin derives from the ability of the founding family member meteorin to transform glia into cells containing an extensive, meteor-like tail. It is expressed by neurons, and appears to function as a primer molecule that sets the stage for either cell differentiation or neurite outgrowth when it acts with Dclk1 and SerpinB1. Mature human METRNL is 266 amino acids (aa) in length (aa 46-311). It reportedly contains a signal sequence (aa 1-45), which suggests it may be secreted. Mature human and mouse METRNL share 79% aa sequence identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Uniprot:
  • Q641Q3()