MERIT40/HSPC142 Antibody [Alexa Fluor® 405]

Product Discontinued

MERIT40/HSPC142 Antibody [Alexa Fluor® 405] Summary

• Immunogen: Produced in rabbits immunized with E. coli-derived Human MERIT40/HSPC142 fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: BABAM1
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MERIT40/HSPC142 Antibody [Alexa Fluor® 405]

• BABAM1
• BRISC and BRCA1 A complex member 1
• C10orf62
• C19orf62
• chromosome 19 open reading frame 62
• FLJ20571
• HSPC142
• mediator of Rap80 interactions and targeting 40 kDa
• Mediator of RAP80 interactions and targeting subunit of 40 kDa
• MERIT40
• MERIT40BRCA1-A complex subunit MERIT40
• NBA1
• NBA1BRISC and BRCA1 A complex member
• new component of the BRCA1 A complex
• New component of the BRCA1-A complex
• new component of the BRCAA1 A complex

Background

HSPC142 is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRC

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BABAM1