Human Melanocortin-1 R/MC1R - Ready-To-Use ELISA Kit (Colorimetric)

ELISA: Human Melanocortin-1 R/MC1R - Ready-To-Use ELISA Kit (Colorimetric) [NBP3-39870] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids
• Standard Curve Range: 15.6 - 1000 pg/mL (example only; lot dependent)
• Sensitivity: 6.43 pg/mL (example only; lot dependent)

Human Melanocortin-1 R/MC1R - Ready-To-Use ELISA Kit (Colorimetric) Summary

• Description: The Ready-To-Use ELISA kit offers pre-diluted detection reagents and a shorter experimental time.
  Assay Length: 3 hours
• Standard Curve Range: 15.6 - 1000 pg/mL (example only; lot dependent)
• Sensitivity: 6.43 pg/mL (example only; lot dependent)
• Assay Type: Competitive ELISA
• Inter-Assay: %CV < 12 (example only; lot dependent)
• Intra-Assay: %CV < 10 (example only; lot dependent)
• Sample Volume: 50 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: MC1R

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human Melanocortin-1 R/MC1R - Ready-To-Use ELISA Kit (Colorimetric)

• CMM5
• MC1R
• MC1-R
• melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
• Melanocortin receptor 1
• Melanocortin-1 R
• Melanocortin1R
• Melanocortin-1R
• melanocyte-stimulating hormone receptor
• melanotropin receptor
• MSHR
• MSH-R
• Mshra
• MSH-RMGC14337
• SHEP2
• Tob

Background

MC1R, a Melanocortin Receptor, mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). MSH and its receptor, MC1R, are key regulators of melanogenesis. They control the relative proportions of red pheomelanin and black photoprotective eumelanin in the skin by increasing the production of eumelanin. Non-functional, truncated forms of the receptor lead to lighter coat color in animals. In contrast, constitutively active receptors lead to darker color. Pheomelanin generates free radicals in response to UV radiation, and elevated levels of pheomelanin have been associated with higher risk of UV-induced skin damage. Therefore, MC1R is a major determinant of sun sensitivity and genetic risk for melanoma and other skin cancers. Expression of melanocortin 1 receptor has been reported primarily in adrenal, skin, and testis. ESTs have been isolated from breast, placenta, and testis libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: MC1R