MCCC2 Antibody

Western Blot: MCCC2 Antibody [H00064087-B01P] - Analysis of MCCC2 expression in human liver.

Immunocytochemistry/Immunofluorescence: MCCC2 Antibody [H00064087-B01P] - Analysis of purified antibody to MCCC2 on HeLa cell. (antibody concentration 10 ug/ml)

Western Blot: MCCC2 Antibody [H00064087-B01P] - Analysis of MCCC2 expression in HepG2.

Western Blot: MCCC2 Antibody [H00064087-B01P] - Analysis of MCCC2 expression in transfected 293T cell line by MCCC2 polyclonal antibody. Lane 1: MCCC2 transfected lysate(61.93 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

MCCC2 Antibody Summary

• Immunogen: MCCC2 (NP_071415.1, 1 a.a. - 563 a.a.) full-length human protein. MWAVLRLALRPCARASPAGPRAYHGDSVASLGTQPDLGSALYQENYKQMKALVNQLHERVEHIKLGGGEKARALHISRGKLLPRERIDNLIDPGSPFLELSQFAGYQLYDNEEVPGGGIITGIGRVSGVECMIIANDATVKGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGAYLPRQADVFPDRDHFGRTFYNQAIMSSKNIAQIAVVMGSCTAGGAYVPAMADENIIVRKQGTIFLAGPPLVKAATGEEVSAEDLGGADLHCRKSGVSDHWALDDHHALHLTRKVVRNLNYQKKLDVTIEPSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTGFARIFGYPVGIVGNNGVLFSESAKKGTHFVQLCCQRNIPLLFLQNITGFMVGREYEAEGIAKDGAKMVAAVACAQVPKITLIIGGSYGAGNYGMCGRAYSPRFLYIWPNARISVMGGEQAANVLATITKDQRAREGKQFSSADEAALKEPIIKKFEEEGNPYYSSARVWDDGIIDPADTRLVLGLSFSAALNAPIEKTDFGIFRM
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: MCCC2
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: This antibody is useful for Western Blot, Immunofluorescence

Reactivity Notes

This product is reactive against Human.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for MCCC2 Antibody

• 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta
• MCCase subunit beta
• MCCBEC 6.4.1.4
• methylcrotonoyl-CoA carboxylase 2 (beta)
• methylcrotonoyl-Coenzyme A carboxylase 2 (beta)
• mitochondrial
• non-biotin containing subunit of 3-methylcrotonyl-CoA carboxylase

Background

This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for MCCC2 Antibody (H00064087-B01P)(1)

Publication using H00064087-B01P

• Grunert SC, Stucki M, Morscher RJ et al. 3-Methylcrotonyl-CoA Carboxylase Deficiency: Clinical, biochemical, enzymatic and molecular studies in 88 individuals. Orphanet J Rare Dis. 2012-05-29 [PMID: 22642865]

Bioinformatics

• Gene Symbol: MCCC2
• Uniprot:
  • NP_071415.1(Human)