MARVELD1 Antibody - BSA Free

Western Blot: MARVELD1 Antibody [NBP1-76243] - Mouse heart tissue lysate with MARVELD1 antibody at (A) 1 and (B) 2 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

MARVELD1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit MARVELD1 Antibody - BSA Free (NBP1-76243) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human MARVELD1. The immunogen is located within the first 50 amino acids of MARVELD1. Amino Acid Squence: PPPRQPPPQARAARGA
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MARVELD1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1-2 ug/ml
• Theoretical MW: 19 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control Peptide:

  MARVELD1 Peptide (NBP1-76243PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for MARVELD1 Antibody - BSA Free

• bA548K23.8
• FLJ22343
• FLJ23440
• GB14
• MARVD1
• MARVEL (membrane-associating) domain containing 1
• MARVEL domain containing 1
• MGC4415
• MRVLDC1
• putative MARVEL domain-containing protein 1
• RP11-548K23.8

Background

MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MARVELD1
• Entrez:
  • 83742(Human)
  • 277010(Mouse)
  • 309375(Rat)
• Uniprot:
  • Q9BSK0(Human)