Marapsin/Pancreasin Antibody (243305) [Alexa Fluor™ Plus 680]

• Reactivity: Hu
• Clone: 243305
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 680

Marapsin/Pancreasin Antibody (243305) [Alexa Fluor™ Plus 680] Summary

• Specificity: Detects human Marapsin/Pancreasin in direct ELISAs and Western blots. Reacts with an epitope within the mature chain. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse Marapsin is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Marapsin/Pancreasin Antibody (243305) [Alexa Fluor™ Plus 680]

• CAP-2
• CAPH2
• channel-activating protease 2
• EC 3.4.21
• EC 3.4.21.-
• EC 3.4.21.4
• EC 3.4.21.43
• Marapsin
• MPN
• MPNMarapsin
• Pancreasin
• protease, serine 27
• PRSS27
• serine protease 27

Background

Marapsin, pancreasin, and channel-activating protease 2 (CAP-2) are different names for the same serine protease that is expressed strongly in the pancreas (1, 2). The protein is synthesized with a signal peptide (amino acids 1‑22), a pro peptide (aa 23‑34) and a mature chain (aa 35‑290) corresponding to the serine protease domain.

1. Bhagwandin, V.J. et al. (2003) J. Biol. Chem. 278:3363.
2. Edwards, K.M. et al. (1999) J. Biol. Chem. 274:30468.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.