LPAR1/LPA1/EDG-2 Antibody

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Immunohistochemistry-Paraffin: LPAR1/LPA1/EDG-2 Antibody [NLS212] - Analysis of anti-EDG2 antibody with human brain, glia.

Product Details

Summary
Reactivity Hu, Mk, Pm, Mu, Rt, Po, Bt, Bv, Ca, Ch, Eq, Ha, Op, Rb, Sh, TrSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

LPAR1/LPA1/EDG-2 Antibody Summary

Immunogen
Synthetic 15 amino acid peptide from N-terminal extracellular domain of human EDG2.
Localization
Cell Membrane
Specificity
Human EDG2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DDX60 (53%), ACER3 (47%).
Predicted Species
Mouse (93%), Rat (93%), Porcine (93%), Bovine (93%), Rabbit (93%), Opossum (93%), Hamster (93%), Chicken (93%), Canine (93%), Bat (93%), Sheep (93%), Turkey (93%), Equine (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
LPAR1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:10-1:500
Publications
Read Publications using
NLS212 in the following applications:

Reactivity Notes

Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (100%), Panda (93%), Platypus (93%), Xenopus (87%), Pufferfish (87%), Zebrafish (87%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for LPAR1/LPA1/EDG-2 Antibody

  • EDG2
  • edg-2
  • EDG2Lysophosphatidic acid receptor Edg-2
  • endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor2,
  • GPCR26
  • GPR26
  • LPA receptor 1
  • LPA1
  • LPA-1
  • LPA1vzg-1
  • LPAR1
  • lysophosphatidic acid receptor 1
  • Mrec1.3
  • rec.1.3
  • ventricular zone gene 1
  • VZG1
  • vzg-1

Background

Edg2, a Lysophospholipid/Lysosphingolipid Receptor, mediates growth factor-like activities such as proliferation, platelet aggregation, and chemotaxis. Edg2 is involved in myelin formation or maintenance. It is activated by platelet-derived lysophosphatidic acid (LPA), a lipid metabolite present in serum that acts ubiquitously. Although alternate translation start codons and polyadenylation sites have been reported, the alternative splicing transcripts each encode identical proteins. Edg2 has been reported in most human tissues, and is especially abundant in brain cortical regions. ESTs have been isolated from bone, brain, breast, connective tissue, embryo, heart/melanocyte/uterus, lung, prostate, and uterus libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for LPAR1/LPA1/EDG-2 Antibody (NLS212)(2)

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Bioinformatics

Gene Symbol LPAR1
Entrez
Uniprot