Limitin/IFN-zeta Antibody (183707)

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA(Cap), Neut
Clone
183707
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated

Order Details

Limitin/IFN-zeta Antibody (183707) Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Limitin/IFN‑ zeta
Leu22-Arg182
Accession # Q9R1T0
Specificity
Detects mouse Limitin/IFN‑ zeta in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse IFN-gamma is observed.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
Ifnz
Purity
Protein A or G purified from hybridoma culture supernatant
Endotoxin Note
<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
  • ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL
  • Neutralization 0.02-0.1 ug/mL
  • ELISA Standard (Matched Pair)
Application Notes
ELISA Detection: Mouse Limitin/IFN-zeta Biotinylated Affinity Purified PAb (Catalog number BAF597)
Standard: Recombinant Mouse Limitin/IFN-zeta (Catalog number 1535-LM)

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Purity
Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Limitin/IFN-zeta Antibody (183707)

  • 6030405N23Rik
  • BGIF
  • Ifnz
  • IFN-z
  • IFNzeta
  • interferon zeta
  • Limitin
  • Lmtn

Background

Limitin is a secreted interferon (IFN)-like glycoprotein. It has antiviral activity and selectively inhibits B-lineage lymphoid-cell development both in vivo and in vitro, while having little effect on myelopoiesis or erythropoiesis. Limitin binds to the IFN-alpha/beta receptors and induces IFN regulatory factor-1. Mouse limitin displays 32%, 26% and 30% amino acid sequence identity with mouse IFN-alpha, mouse IFN-beta, and human IFN-omega, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol Ifnz
Entrez
Uniprot