Limitin/IFN-zeta Antibody (183707)

• Reactivity: Mu
• Applications: B/N, ELISA(Cap)
• Clone: 183707
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated

Limitin/IFN-zeta Antibody (183707) Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Limitin/IFN‑ zeta
  Leu22-Arg182
  Accession # Q9R1T0
• Specificity: Detects mouse Limitin/IFN‑ zeta in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse IFN-gamma is observed.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: Ifnz
• Purity Statement: Protein A or G purified from hybridoma culture supernatant
• Endotoxin Note: <0.10 EU per 1 μg of the antibody by the LAL method.

Applications/Dilutions

• Dilutions:
  • ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
  • ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL
  • ELISA Standard (Matched Pair)
  • Neutralization 0.02-0.1 ug/mL
• Application Notes: ELISA Detection: Mouse Limitin/IFN-zeta Biotinylated Affinity Purified PAb (Catalog number BAF597)
  Standard: Recombinant Mouse Limitin/IFN-zeta (Catalog number 1535-LM)

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Limitin/IFN-zeta Antibody (183707)

• 6030405N23Rik
• BGIF
• Ifnz
• IFN-z
• IFNzeta
• interferon zeta
• Limitin
• Lmtn

Background

Limitin, also known as IFN-zeta , is a 20 kDa glycoprotein that is secreted by T cells and bronchial and salivary duct epithelial cells. It inhibits B-lineage cell development but has little effect on myelopoiesis or erythropoiesis. Limitin binds to IFN-alpha / beta receptors and has potent antiviral activity. Mouse Limitin shares 32%, 26%, and 30% amino acid sequence identity with mouse IFN-alpha , mouse IFN-beta , and human IFN-omega , respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: Ifnz
• Uniprot:
  • Q9R1T0()