LGTN Antibody [Janelia Fluor® 635]

Product Discontinued

LGTN Antibody [Janelia Fluor® 635] Summary

• Immunogen: The immunogen for this product maps to a region between residue 350 and 400 of human eIF2D using the numbering given in entry NP_008824.2 (GeneID 1939).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: EIF2D
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for LGTN Antibody [Janelia Fluor® 635]

• eukaryotic translation initiation factor 2D
• HCA56eIF2d
• Hepatocellular carcinoma-associated antigen 56
• LGTNLigatin
• ligatin

Background

LGTN encodes a protein receptor that localizes phosphoglycoproteins within endosomes and at the cell periphery. This trafficking receptor for phosphoglycoproteins may play a role in neuroplasticity by modulating cell-cell interactions, intracellular adhesion, and protein binding at membrane surfaces. In hippocampal neurons, long-lasting down-regulation of ligatin mRNA levels occurs via post-transcriptional RNA processing following glutamate receptor activation. This protein contains single PUA and SUI1 domains and these domains may function in RNA binding and translation initiation, respectively. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EIF2D