Lactalbumin Alpha Antibody (F20.16) - BSA Free

Product Discontinued

Lactalbumin Alpha Antibody (F20.16) - BSA Free Summary

• Immunogen: Purified casein and Lactalbumin Alpha
• Localization: Secreted
• Specificity: alpha Lactalbumin (F20.16)
• Isotype: IgM
• Clonality: Monoclonal
• Host: Mouse
• Gene: LALBA
• Purity: Thiophilic Chromatography

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 1:10-1:2000
  • Immunohistochemistry
  • Western Blot 1:100-1:2000
• Application Notes: Western Blot detects a band of approximately 14 kDa
• Theoretical MW: 14 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control:

  Lactalbumin Alpha Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Thiophilic Chromatography

Alternate Names for Lactalbumin Alpha Antibody (F20.16) - BSA Free

• alpha-lactalbumin
• lactalbumin, alpha-
• Lactose synthase B protein
• Lysozyme-like protein 7
• LYZL7
• MGC138521
• MGC138523

Background

alpha Lactalbumin is the B protein of lactose synthetase secreted by the mammary epithelial cells. alpha Lactalbumin is a potent Ca2+-elevating and apoptosis-inducing agent with broad, yet selective, cytotoxic activity. Multimeric alpha Lactalbumin killed all transformed, embryonic, and lymphoid cells tested but spared mature epithelial elements. It suggests that milk contributes to mucosal immunity not only by furnishing antimicrobial molecules but also by policing the function of lymphocytes and epithelium. alpha Lactalbumin may be helpful in ascertaining the site of origin of metastatic breast tumors. This antibody can be used as an in vitro marker of terminally differentiated breast lumenal epithelial cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Lactalbumin Alpha Antibody (NB100-2783)(1)

Publication using NB100-2783

• Koning N, Kessen SF, Van Der Voorn JP et al. Human Milk Blocks DC-SIGN-Pathogen Interaction via MUC1. Front Immunol. 2015-03-30 [PMID: 25821450] (ELISA, Human)

Bioinformatics

• Gene Symbol: LALBA
• Entrez:
  • 3906(Human)
• Uniprot:
  • P00709(Human)