L1TD1 Antibody (901258)

Images

 
Western blot shows lysates of BG01V human embryonic stem cells and NTera-2 human testicular embryonic carcinoma cell line. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human L1TD1 Monoclonal Antibody (Catalog # ...read more
L1TD1 was detected in immersion fixed BG01V human embryonic stem cells, undifferentiated (upper panel) or differentiated for 4 days (lower panel), using Mouse Anti-Human L1TD1 Monoclonal Antibody (Catalog # MAB8317) at ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clone
901258
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price

L1TD1 Antibody (901258) Summary

Immunogen
E. coli-derived recombinant human L1TD1
Met1-Leu142
Accession # Q5T7N2
Specificity
Detects human L1TD1 in direct ELISAs and Western blots.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
L1TD1
Purity
Protein A or G purified from hybridoma culture supernatant
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry 8-25 ug/mL
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for L1TD1 Antibody (901258)

  • ECAT11
  • ES cell-associated protein 11
  • FLJ10884
  • L1TD1
  • LINE-1 type transposase domain containing 1
  • LINE-1 type transposase domain-containing protein 1
  • MGC133253
  • RP5-1155K23.3

Background

L1TD1 (LINE-1 type transposase domain-containing protein 1; also known as ES cell-associated protein 11 and FLJ10884) is an RNA binding protein with a reported molecular weight of approximately 100 kDa.  It is 865 amino acids (aa) in length and shares 43% aa identity with mouse L1TD1.  L1TD1 is a marker for undifferentiated pluripotent stem cells.  Knock down of its expression in these cells has been shown to decrease the expression of critical pluripotency factors such as Nanog and Oct-3/4.  L1TD1 function in stem cells is likely regulated by its interaction with factors such as LIN-28 and is suggested to regulate RNA processing.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

Additional L1TD1 Products

Array MAB8317

Bioinformatics Tool for L1TD1 Antibody (MAB8317)

Discover related pathways, diseases and genes to L1TD1 Antibody (MAB8317). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for L1TD1 Antibody (MAB8317)

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Bioinformatics

Gene Symbol L1TD1
Uniprot