Kv3.4 Antibody

Product Discontinued

Kv3.4 Antibody Summary

• Immunogen: A synthetic peptide from c-terminal region of human KCNC4 (Kv3.4) conjugated to an immunogenic carrier protein was used as the antigen.
• Specificity: Specific for KCNC4.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KCNC4
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot 1:200-1:2000

Reactivity Notes

Human, rat, mouse. Other species not yet tested.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Whole antisera
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Unpurified
• Reconstitution Instructions: Please contact technical support for detailed reconstituion instruction.

Notes

Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Alternate Names for Kv3.4 Antibody

• HKSHIIIC
• K+ channel subunit
• KSHIIIC
• KV3.4
• MGC126818
• potassium voltage-gated channel subfamily C member 4
• potassium voltage-gated channel, Shaw-related subfamily, member 4
• Voltage-gated potassium channel subunit Kv3.4

Background

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Kv3.4, a member of the Shaw subfamily, may play important roles in maintaining normal function of the corneal epithelium. Also, it is over-expressed in the early stages of Alzheimer’s disease, and, therefore, represents a novel therapeutic target for that disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KCNC4
• Entrez:
  • 3749(Human)