Kv1.3 Antibody

Product Discontinued

Kv1.3 Antibody Summary

• Immunogen: Synthetic peptide, corresponding to amino acids 100-150 of Human Kv1.3.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KCNA3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200

Reactivity Notes

Human, Mouse and Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Kv1.3 Antibody

• HGK5
• HLK3
• HLK3KV1.3
• HPCN3
• HPCN3PCN3
• HUKIII
• KCNA3
• Kv1.3
• MK3
• potassium channel 3
• potassium voltage-gated channel subfamily A member 3
• potassium voltage-gated channel, shaker-related subfamily, member 3
• type n potassium channel
• Voltage-gated K(+) channel HuKIII
• voltage-gated potassium channel protein Kv1.3
• Voltage-gated potassium channel subunit Kv1.3

Background

KCNA3 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Kv1.3 Antibody (NBP1-19415)(1)

Publication using NBP1-19415

• Koch Hansen Lars, Sevelsted-Moller Linda, Rabjerg Maj et al. Expression of T-cell KV1.3 potassium channel correlates with pro-inflammatory cytokines and disease activity in ulcerative colitis. J Crohns Colitis. 2014-11-01 [PMID: 24793818]

Bioinformatics

• Gene Symbol: KCNA3
• Entrez:
  • 3738(Human)
  • 16491(Mouse)
  • 29731(Rat)
• Uniprot:
  • P22001(Human)