Kv1.2 Antibody [FITC]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Ca, Xp, ZeSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
FITC

Kv1.2 Antibody [FITC] Summary

Immunogen
Synthetic peptide made to a portion of rat Kv1.2 (within residues 50-100). [Swiss-Prot# P63142]
Localization
Membrane; Multi-pass membrane protein
Specificity
Does not cross-react with Kv3.1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KCNA2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence
Application Notes
This Kv1.2 antibody is useful for Immunocytochemistry/Immunofluorescence, Immunoprecipitation and Western blot, where a band can be seen at ~80 kDa.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
80 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human, mouse, rat, bovine, porcine, canine, Xenopus, Zebrafish and other vertebrates.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Kv1.2 Antibody [FITC]

  • EC 3.6.1.27
  • EC 6.1.1
  • HBK5
  • HK4
  • HUKIV
  • KV1.2
  • MGC50217
  • MK2
  • NGK1
  • potassium channel
  • potassium voltage-gated channel subfamily A member 2
  • potassium voltage-gated channel, shaker-related subfamily, member 2
  • RBK2
  • Voltage-gated K(+) channel HuKIV
  • Voltage-gated potassium channel HBK5
  • voltage-gated potassium channel protein Kv1.2
  • Voltage-gated potassium channel subunit Kv1.2

Background

Kv1.2 (KCNA2, Potassium voltage-gated channel subfamily A member 2) mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which K(+) ions may pass in accordance with their electrochemical gradient. Kv1.2 binds PDZ domains of DLG1, DLG2 and DLG4. The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments. The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KCNA2