KSR1 Antibody (MINT/1/4)

Product Discontinued

KSR1 Antibody (MINT/1/4) Summary

• Immunogen: Recombinant human KSR protein.
• Specificity: This recognises the kinase suppressor of Ras (KSR).
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: KSR1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1:100-1:2000
• Application Notes: IHC-Fr: Use at an assay dependent dilution. M-P: Use at an assay dependent dilution. Methacarn fixation recommended for paraffin embedded tissues. WB: Use at an assay dependent dilution. Predicted molecular weight: 140 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.

Reactivity Notes

Reacts with Human. Cross reacts with Mouse and Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: No buffer
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein G purified

Alternate Names for KSR1 Antibody (MINT/1/4)

• kinase suppressor of ras 1
• kinase suppressor of ras
• KSRRSU2

Background

Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KSR1
• Entrez:
  • 8844(Human)
  • 16706(Mouse)
  • 360573(Rat)