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KOR Antibody - BSA Free

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Western Blot: Kappa Opioid Receptor Antibody [NB110-79876] - WB detection of Kappa Opioid Receptor / KOR-1 in 10 ug of human brain lysate (lane 1) and rat brain lysate (lane 2) with this antibody at a dilution of 1:500.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

KOR Antibody - BSA Free Summary

Immunogen
Synthetic peptide comprising residues 366-380 of the human KOR-1 protein. Sequence identity is 66% in mouse and rat.
Specificity
Kappa Opioid Receptor
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
OPRK1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
Western Blot

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human and rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for KOR Antibody - BSA Free

  • kappa opioid receptor
  • kappa-type opioid receptor
  • KOR
  • K-OR-1
  • KOR-1
  • Opiate receptor, kappa-1
  • opioid receptor, kappa 1
  • OPRK
  • OPRK1
  • Oprk2
  • R21

Background

G protein-coupled receptors (GPCRs) are the largest family of membrane receptors that activate intracellular signaling cascades and undergo endocytosis, recycling, or degradation upon stimulation. The (mu), delta and kappa opioid receptors are GPCRs of the nervous system, which control pain, stress, and addictive behaviors. The kappa opioid receptor (KOR-1) plays a role in arousal and regulation of autonomic and neuroendocrine functions and is the receptor for dynorphins. KOR-1 inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol OPRK1
Entrez