KDM2B Antibody

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Immunohistochemistry-Paraffin: KDM2B Antibody [NB100-1293] - Staining of paraffin embedded Human Skin. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC-P, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

KDM2B Antibody Summary

Immunogen
Peptide with sequence C-FGQVEEKLLQKLS corresponding to C-Terminus according to NP_115979.3.
Specificity
This antibody is expected to recognize isoform a (NP_115979.3) only.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
KDM2B
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 - 3 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Peptide ELISA Detection limit 1:32000
Application Notes
WB: An anonymous customer has reported bands at approx. 170+90 kDa band in lysates HeLa (calculated MW of 153 kDa band according to NP_115979.3).
Publications
Read Publication using NB100-1293.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Rat, Canine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for KDM2B Antibody

  • [Histone-H3]-lysine-36 demethylase 1B
  • CXXC2F-box protein FBL10
  • CXXC-type zinc finger protein 2
  • Fbl10
  • F-box and leucine-rich repeat protein 10JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein
  • FBXL10
  • JHDM1BF-box/LRR-repeat protein 10
  • JmjC domain-containing histone demethylation protein 1B
  • jumonji C domain-containing histone demethylase 1B
  • Jumonji domain-containing EMSY-interactor methyltransferase motif protein
  • lysine (K)-specific demethylase 2B
  • lysine-specific demethylase 2B
  • PCCX2EC 1.14.11.27
  • protein containing CXXC domain 2
  • Protein JEMMA
  • Protein-containing CXXC domain 2

Background

Fbxl10 (PCCX2) encodes a nuclear protein carrying a PHD finger, a CXXC domain, and an acidic region. The CXXC domain was found to be sufficient for binding to DNA. The acidic region exhibits a high transactivation ability, but the full-length protein was inactive due to regions which inhibited the acidic region, including the C-terminal region. PCCX1 is activated by proteolytic cleavage, which removes the C-terminal inhibitory region.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for KDM2B Antibody (NB100-1293)(1)

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KDM2B
Entrez
Uniprot