KDM2B Products

Description

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.

Bioinformatics

Entrez	84678 Human
Uniprot	NP_115979 Human
Product By Gene ID	84678
Alternate Names	[Histone-H3]-lysine-36 demethylase 1B CXXC2 CXXC2F-box protein FBL10 CXXC-type zinc finger protein 2 FBL10 F-box and leucine-rich repeat protein 10JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein F-box protein FBL10 FBXL10 JHDM1B JHDM1BF-box/LRR-repeat protein 10 JmjC domain-containing histone demethylation protein 1B jumonji C domain-containing histone demethylase 1B Jumonji domain-containing EMSY-interactor methyltransferase motif protein KDM2B lysine (K)-specific demethylase 2B lysine-specific demethylase 2B NDY1 PCCX2 PCCX2EC 1.14.11.27 protein containing CXXC domain 2 Protein JEMMA Protein-containing CXXC domain 2