KCNA7 Antibody

Product Discontinued

KCNA7 Antibody Summary

• Immunogen: This antibody was developed against a recombinant protein corresponding to amino acids: PAPLNGSSQMPGNPPRLPFNDPF
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KCNA7
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for KCNA7 Antibody

• HAK6
• KCNA7
• KV1.7
• potassium voltage-gated channel subfamily A member 7
• potassium voltage-gated channel, shaker-related subfamily, member 7
• voltage-dependent potassium channel Kv1.7
• voltage-gated potassium channel KCNA7
• Voltage-gated potassium channel subunit Kv1.7

Background

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. The gene is expressed preferentially in skeletal muscle, heart and kidney. It is a candidate gene for inherited cardiac disorders.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KCNA7
• Uniprot:
  • Q96RP8(Human)