JNK2 Antibody

Western Blot: JNK2 Antibody [NB600-1297] - Western blot analysis for JNK2 using NB600-1297 at 2 ug/ml on 20 ugs of A431 whole cell lysate.

Product Discontinued

JNK2 Antibody Summary

• Immunogen: A synthetic peptide corresponding to amino acids 373-389 (KDQPSDAAVSSNATPSQ) of human JNK2 was used as immunogen; GenBank no. gi|21237736|ref|NP_002743.3|. This amino sequence is 100% homologous in cow and dog, and 94% in mouse and rat.
• Localization: Nuclear
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MAPK9
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1-3 ug/ml
• Application Notes: Western Blot: Predicted molecular weight: 51 kDa.
• Control:

  A-431 Whole Cell Lysate

Reactivity Notes

Cross-reacts with Human. Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS containing 0.2% gelatin
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein G purified

Alternate Names for JNK2 Antibody

• c-Jun kinase 2
• c-Jun N-terminal kinase 2
• EC 2.7.11
• EC 2.7.11.24
• JNK2
• JNK2A
• JNK2BETA
• JNK2JNK2ALPHA
• JNK-55
• Jun kinase
• MAP kinase 9
• MAPK 9
• MAPK9
• mitogen-activated protein kinase 9
• p54a
• p54aSAPK
• PRKM9JNK2B
• SAPK
• SAPK1 alpha
• Stress-activated protein kinase JNK2

Background

c-Jun amino terminal kinases (JNKs) are MAP kinase family members that differ from other MAP kinases in that they are phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53. This antibody recognizes JNK2; human JNK2 is a 424 amino acid protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAPK9
• Uniprot:
  • P45984(Human)