ISLR-2 Antibody

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Sheep
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price

ISLR-2 Antibody Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human ISLR-2
Cys20-Leu590
Accession # Q6UXK2
Specificity
Detects human ISLR-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 25% cross-reactivity with recombinant human ISLR-2 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Sheep
Gene
ISLR2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.1 ug/mL
Publications
Read Publication using
AF4526 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Immunogen affinity purified
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ISLR-2 Antibody

  • immunoglobulin superfamily containing leucine-rich repeat 2
  • ISLR2
  • ISLR-2
  • KIAA1465
  • leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein
  • LINX
  • UNQ1885/PRO4329

Background

ISLR-2 (Ig-superfamily containing LRR protein 2; also KIAA1465) is a 100‑110 kDa member of the LRR family of proteins. It is expressed on developing motor, sensory and interneurons. Mature human ISLR-2 is 727 amino acids (aa) in length. It is a type I transmembrane glycoprotein that contains a 571 aa extracellular domain (ECD) and a 135 aa cytoplasmic region. The ECD shows multiple LRRs (aa 50‑227) and one Ig-like domain (aa 233‑371). One alternate splice form may exist that shows a deletion of aa 160‑570. Over aa 20‑590, human ISLR-2 is 89% aa identical to both canine and mouse ISLR-2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ISLR-2 Antibody (AF4526)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


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WB
(1)
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Video Protocols

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Bioinformatics

Gene Symbol ISLR2
Entrez
Uniprot