ISG15 Activating Enzyme/UBE1L Antibody Pair

Product Discontinued

ISG15 Activating Enzyme/UBE1L Antibody Pair Summary

• Description: Quality control test: Immunoprecipitation-Western Blot (IP-WB). This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  
  
• Antibody pair for IP: rabbit polyclonal anti-UBA7 (300 ul)
• Antibody pair for WB: mouse purified polyclonal anti-UBA7 (50 ug)
• Clonality: Polyclonal
• Gene: UBA7
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ISG15 Activating Enzyme/UBE1L Antibody Pair

• D8
• D8UBA1, ubiquitin-activating enzyme E1 homolog B
• ISG15 Activating Enzyme/UBE1L
• UBA1B
• UBA7
• UBA7, ubiquitin-activating enzyme E1
• UBE1L
• UBE2
• UBE2MGC12713
• Ubiquitin-activating enzyme 7
• Ubiquitin-activating enzyme E1 homolog
• ubiquitin-activating enzyme E1-like
• ubiquitin-activating enzyme E1-related protein
• ubiquitin-activating enzyme-2
• ubiquitin-like modifier activating enzyme 7
• ubiquitin-like modifier-activating enzyme 7

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: UBA7