IRGM Antibody Blocking Peptide

• Reactivity: Hu
• Applications: AC
• Concentration: 0.2 mg/ml

IRGM Antibody Blocking Peptide Summary

• Description: A blocking peptide containing 14 amino acids near the center of human IRGM.

  Source: Synthetic

  (Accession #: AAI28169)

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: IRGM
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-76890.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
• Preservative: 0.02% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: N/A

Alternate Names for IRGM Antibody Blocking Peptide

• IFI1
• immunity-related GTPase family M protein
• immunity-related GTPase family, M
• interferon-inducible protein 1
• IRGM1
• LPS-stimulated RAW 264.7 macrophage protein 47 homolog
• LRG47
• LRG-47
• LRG-47-like protein
• M1
• MGC149263
• MGC149264

Background

Members of the p47 immunity-related GTPase (IRG) family, including IRGM, play an important role in the murine immune system; however, in humans this resistance system is greatly reduced. There is evidence that human IRGM plays a role in autophagy and control of intracellular mycobacteria (Bepken et al., 2005; Singh et al., 2006 [PubMed 16888103]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: IRGM