Intersectin 2 Antibody

Western Blot: Intersectin 2 Antibody [H00050618-A01] - Detection against Immunogen (37.22 KDa) .

Product Discontinued

Intersectin 2 Antibody Summary

• Immunogen: ITSN2 (NP_006268, 471 a.a. - 571 a.a.) partial recombinant protein with GST tag. NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSN
• Specificity: ITSN2 - intersectin 2
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: ITSN2
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:500
• Application Notes: The quality control of this antibody is limited to Western blot on the immunizing protein. It has also been used for ELISA. Abnova's recommended working dilutions for western analysis are as follows: 1:500 dilution for ascites 1:1000 for purified Ig 1:500

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 50% Glycerol
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Intersectin 2 Antibody

• intersectin 2
• KIAA1256SH3 domain-containing protein 1B
• PRO2015
• SH3 domain protein 1B
• SH3P18-like WASP associated protein
• SH3P18SH3D1Bintersectin-2
• SWA
• SWAPSH3P18-like WASP-associated protein

Background

This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. Alternatively spliced transcript variants have been found for this gene that encode three distinct isoforms. Additional variants have been found but their full length nature has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Intersectin 2 Antibody (H00050618-A01)(1)

Publication using H00050618-A01

• Rodriguez-Fraticelli AE, Vergarajauregui S, Eastburn DJ et al. The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis. [PMID: 20479469]

Bioinformatics

• Gene Symbol: ITSN2
• Entrez:
  • 50618(Human)
• OMIM:
  • 604464(Human)
• Uniprot:
  • NP_006268(Human)