Integrin alpha 2/CD49b Antibody - BSA Free

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody - BSA Free [NB110-55540] - Analysis of anti-ITGA2 / CD49b antibody with human colon, surface epithelium at concentration 10 ug/ml.

Product Discontinued

Integrin alpha 2/CD49b Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 14 amino acid peptide from extracellular domain of human Integrin alpha 2/CD49b.
• Epitope: Extracellular domain of human
• Marker: Plasma Membrane Marker
• Specificity: Human Integrin alpha 2/CD49b. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Mouse (93%), Bovine (93%), Primate (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ITGA2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (100%), Gorilla (93%), Marmoset (93%), Rat (86%), Porcine (86%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Integrin alpha 2/CD49b Antibody - BSA Free

• alpha-2 subunit
• CD49b antigen
• CD49b
• Integrin alpha 2
• integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
• ITGA2
• VLA 2
• VLA-2 alpha

Background

ITGA2 encodes integrin alpha chain 2. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing alpha integrin 2 combines with beta integrin 1 to form a collagen-binding integrin referred to as glycoprotein Ia/IIa when expressed on platelets, and very late (activation) antigen 2 ('VLA-2') when found on T-cells. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ITGA2
• Entrez:
  • 3673(Human)