Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Monoclonal
Flow, IP, CyTOF-ready, ICC/IFHost:
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Applications: WB, ELISA, PA, AP
Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.
Research Areas for Integrin alpha 2/CD49b
Find related products by research area and learn more about each of the different research areas below.Cellular MarkersSignal Transduction
Bioinformatics Tool for Integrin alpha 2/CD49b
Discover related pathways, diseases and genes to Integrin alpha 2/CD49b. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.