Importin alpha 2/KPNA2 Antibody

Images

 
Western Blot: Importin alpha 2/KPNA2 Antibody [H00003838-B01P] - Analysis of KPNA2 expression in transfected 293T cell line by KPNA2 polyclonal antibody. Lane 1: KPNA2 transfected lysate(58.19 KDa). Lane 2: ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Importin alpha 2/KPNA2 Antibody Summary

Immunogen
KPNA2 (NP_002257.1, 1 a.a. - 529 a.a.) full-length human protein. MSTNENANTPAARLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTVNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESVYKASLSLIEKYFSVEEEEDQNVVPETTSEGYTFQVQDGAPGTFNF
Specificity
KPNA2 - karyopherin alpha 2 (RAG cohort 1, importin alpha 1),
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
KPNA2
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

Quality control test: Antibody reactive against mammalian transfected lysate.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Importin alpha 2/KPNA2 Antibody

  • Importin alpha 1
  • Importin alpha 2
  • importin-alpha-P1
  • IPOA1
  • karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
  • Karyopherin subunit alpha-2
  • KPNA2
  • Pendulin
  • QIP2
  • QIP2importin alpha 2
  • RAG cohort 1
  • RAG cohort protein 1
  • RCH1
  • RCH1importin subunit alpha-2
  • SRP1
  • SRP1alpha
  • SRP1-alpha

Background

The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

H00003836-M01
Species: Hu, Rt
Applications: WB, ELISA, ICC/IF, IHC-P
NBP1-31260
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-74190
Species: Mu
Applications: WB, ChIP
NB100-81650
Species: Hu
Applications: WB, IHC, IHC-P, IP, PLA
NBP1-31776
Species: Hu, Mu
Applications: WB, ICC/IF
MAB8209
Species: Hu, Mu, Rt
Applications: WB, ICC
H00001434-M08
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC-P
NBP1-86960
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-43666
Species: Hu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-85637
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-85383
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
H00008175-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IP
NBP1-91949
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NB100-143
Species: Hu, Mu, Ha, Ma, Pm
Applications: WB, ChIP, Flow, ICC/IF, IHC, IHC-P, IP, KO
AF5745
Species: Hu
Applications: WB, IHC
H00003838-B01P
Species: Hu
Applications: WB

Publications for Importin alpha 2/KPNA2 Antibody (H00003838-B01P) (0)

There are no publications for Importin alpha 2/KPNA2 Antibody (H00003838-B01P).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Importin alpha 2/KPNA2 Antibody (H00003838-B01P) (0)

There are no reviews for Importin alpha 2/KPNA2 Antibody (H00003838-B01P). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Importin alpha 2/KPNA2 Antibody (H00003838-B01P) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Importin alpha 2/KPNA2 Products

Bioinformatics Tool for Importin alpha 2/KPNA2 Antibody (H00003838-B01P)

Discover related pathways, diseases and genes to Importin alpha 2/KPNA2 Antibody (H00003838-B01P). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Importin alpha 2/KPNA2 Antibody (H00003838-B01P)

Discover more about diseases related to Importin alpha 2/KPNA2 Antibody (H00003838-B01P).
 

Pathways for Importin alpha 2/KPNA2 Antibody (H00003838-B01P)

View related products by pathway.

PTMs for Importin alpha 2/KPNA2 Antibody (H00003838-B01P)

Learn more about PTMs related to Importin alpha 2/KPNA2 Antibody (H00003838-B01P).
 

Research Areas for Importin alpha 2/KPNA2 Antibody (H00003838-B01P)

Find related products by research area.

Blogs on Importin alpha 2/KPNA2

There are no specific blogs for Importin alpha 2/KPNA2, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Importin alpha 2/KPNA2 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol KPNA2
Entrez
Uniprot