Importin alpha 2/KPNA2 Products

Antibodies
Importin alpha 2/KPNA2 Antibo ...
Importin alpha 2/KPNA2 Antibody
NB100-79807
Species: Hu, Primate, Monkey
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Importin alpha 2/KPNA2 Antibo ...
Importin alpha 2/KPNA2 Antibody
NBP1-31098
Species: Hu, Primate, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
Importin alpha 2/KPNA2 Overex ...
Importin alpha 2/KPNA2 Overexpress...
H00003838-T01
Species: Hu
Applications: WB
Importin alpha 2/KPNA2 Overex ...
Importin alpha 2/KPNA2 Overexpress...
NBL1-12370
Applications: WB
Proteins
Importin alpha 2/KPNA2 Recomb ...
Importin alpha 2/KPNA2 Recombinant...
NBP2-38482PEP
Species: Hu
Applications: AC
Importin alpha 2/KPNA2 Recomb ...
Importin alpha 2/KPNA2 Recombinant...
NBP1-78888
Species: Hu
Applications: PAGE
Importin alpha 2/KPNA2 Peptid ...
Importin alpha 2/KPNA2 Peptide
NBP1-76298PEP
Species: Hu
Applications: AC
RNAi
Importin alpha 2/KPNA2 RNAi
Importin alpha 2/KPNA2 RNAi
H00003838-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 3838
Alternate Names
  • RAG cohort protein 1
  • SRP1
  • SRP1-alpha
  • RAG cohort 1
  • Karyopherin subunit alpha-2
  • pendulin
  • SRP1alpha
  • importin-alpha-P1
  • IPOA1
  • RCH1importin subunit alpha-2
  • QIP2importin alpha 2
  • importin alpha 1
  • karyopherin alpha 2 (RAG cohort 1, importin alpha 1)

Research Areas for Importin alpha 2/KPNA2

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Cellular Markers
Core ESC-Like Genes
Immunology
Stem Cell Markers

PTMs for Importin alpha 2/KPNA2

Learn more about PTMs related to Importin alpha 2/KPNA2.

Sumoylation
Phosphorylation
Cleavage

Bioinformatics Tool for Importin alpha 2/KPNA2

Discover related pathways, diseases and genes to Importin alpha 2/KPNA2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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