ILT1/CD85h/LILRA2 Antibody (600007) [Alexa Fluor® 532]

• Reactivity: Hu
• Applications: Flow, CyTOF-ready
• Clone: 600007
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

ILT1/CD85h/LILRA2 Antibody (600007) [Alexa Fluor® 532] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human LILRA2/CD85h/ILT1
  Pro17-Ser437
  Accession # Q8N149
• Specificity: Detects human LILRA2/CD85h/ILT1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) ILT2, 3, 4, 5, rhLIR6, or rhLIR8 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: LILRA2
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ILT1/CD85h/LILRA2 Antibody (600007) [Alexa Fluor® 532]

• CD85 antigen-like family member H
• CD85h antigen
• CD85h
• ILT1
• ILT-1
• ILT1CD85H
• Leukocyte immunoglobulin-like receptor 7
• leukocyte immunoglobulin-like receptor subfamily A member 2 soluble
• leukocyte immunoglobulin-like receptor subfamily A member 2
• leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
• LILRA2
• LIR7
• LIR7LIR-7Immunoglobulin-like transcript 1

Background

LILRA2, also known as Leukocyte immunoglobulin-like receptor subfamily A member 2, has a 483 amino acid long isoform that is 53 kDa and a short 466 amino acid isoform that is 51 kDa, acts as an activating receptor for eosinophils that elicited the release of cytotoxic granule proteins, de novo lipid mediator generation, and cytokine release through vesicular transport, but does not bind class I MHC antigens. Studies are being performed in relation to this protein and several diseases and disorders including leprosy, microscopic polyangiitis, systemic lupus, erythematosus, lupus erythematosus, hepatitis c, and hepatitis b. This protein has been shown to interact with EWSR1 and USP46 proteins in osteoclast differentiation, defense response, and signal transduction pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LILRA2