ILT1/CD85h/LILRA2 Antibody (600007) [Allophycocyanin]

Human peripheral blood monocytes were stained with Mouse Anti-Human ILT1/CD85h APC-conjugated Monoclonal Antibody (Catalog # FAB6364A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.

• Reactivity: Hu
• Applications: Flow
• Clone: 600007
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

ILT1/CD85h/LILRA2 Antibody (600007) [Allophycocyanin] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human ILT1/CD85h
  Pro17-Ser437
  Accession # Q8N149
• Specificity: Detects human ILT1/CD85h in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) ILT2, 3, 4, 5, rhLIR6, or rhLIR8 is observed.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: LILRA2
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ILT1/CD85h/LILRA2 Antibody (600007) [Allophycocyanin]

• CD85 antigen-like family member H
• CD85h antigen
• CD85h
• ILT1
• ILT-1
• ILT1CD85H
• Leukocyte immunoglobulin-like receptor 7
• leukocyte immunoglobulin-like receptor subfamily A member 2 soluble
• leukocyte immunoglobulin-like receptor subfamily A member 2
• leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
• LILRA2
• LIR7
• LIR7LIR-7Immunoglobulin-like transcript 1

Background

Immune-Like Transcript 1 (ILT1), also known as Leukocyte Immunoglobulin-like Receptor 7 (LIR-7), Leukocyte Immunoglobulin-like Receptor subfamily A member 2 (LILRA2), and CD85h, is a 51 kDa (unglycosylated) type I transmembrane glycoprotein and member of the leukocyte immunoglobulin-like receptor family. Human ILT1 is synthesized as a 483 amino acid (aa) precursor that contains a 23 aa signal sequence, a 426 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a 13 aa cytoplasmic region. The ECD contains four Ig-like C2-type domains and seven potential sites for N-linked glycosylation. A splice variant produces a second isoform that has a one aa substitution for aa 419-436 in the longer form. There are no murine orthologs for human ILT1. ILT1 may act as a receptor for class I MHC antigens.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LILRA2
• Uniprot:
  • Q8N149(Human)