ILKAP/PP2C delta Antibody

Western Blot: ILKAP/PP2C delta Antibody [H00080895-B01P] - Analysis of ILKAP expression in transfected 293T cell line by ILKAP polyclonal antibody. Lane 1: ILKAP transfected lysate(43.12 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

ILKAP/PP2C delta Antibody Summary

• Immunogen: ILKAP (NP_110395.1, 1 a.a. - 392 a.a.) full-length human protein. MDLFGDLPEPERSPRPAAGKEAQKGPLLFDDLPPASSTDSGSGGPLLFDDLPPASSGDSGSLATSISQMVKTEGKGAKRKTSEEEKNGSEELVEKKVCKASSVIFGLKGYVAERKGEREEMQDAHVILNDITEECRPPSSLITRVSYFAVFDGHGGIRASKFAAQNLHQNLIRKFPKGDVISVEKTVKRCLLDTFKHTDEEFLKQASSQKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGNVRDGRVLGVLEVSRSIGDGQYKRCGVTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDEKIQTREGKSAADARYEAACNRLANKAVQRGSADNVTVMVVRIGH
• Specificity: ILKAP - integrin-linked kinase-associated serine/threonine phosphatase 2C,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: ILKAP
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ILKAP/PP2C delta Antibody

• DKFZp434J2031
• EC 3.1.3.16
• FLJ10181
• ILKAP
• integrin-linked kinase-associated serine/threonine phosphatase 2C
• integrin-linked kinase-associated serine/threonine phosphatase
• MGC4846
• PP2C delta
• PP2C-DELTA
• protein phosphatase 2c, delta isozyme

Background

The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ILKAP/PP2C delta Antibody (H00080895-B01P)(1)

Publication using H00080895-B01P

• Zhou W, Cao H, Yang X et al. Characterization of Nuclear Localization Signal in the N Terminus of ILKAP and its Essential Role in the Down-Regulation of RSK2 Signaling. J Biol Chem. 2013-01-17 [PMID: 23329845]

Bioinformatics

• Gene Symbol: ILKAP
• Entrez:
  • 80895(Human)
• Uniprot:
  • NP_110395.1(Human)