IL-20R alpha Antibody (038) [Janelia Fluor® 669]

• Reactivity: Hu
• Applications: ELISA, IHC
• Clone: 038
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 669

IL-20R alpha Antibody (038) [Janelia Fluor® 669] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-20R alpha (Accession#: NP_055247.3; Met 1-Lys 250).
• Specificity: No cross-reactivity in ELISA with:
  
  Human IFNgR1
  Human IL10RB
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: IL20RA
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for IL-20R alpha Antibody (038) [Janelia Fluor® 669]

• class II cytokine receptor ZCYTOR7
• CRF2-8
• Cytokine receptor class-II member 8
• Cytokine receptor family 2 member 8
• FLJ40993
• IL-20 R alpha
• IL20R alpha
• IL-20R alpha
• IL-20R1
• IL-20R1IL-20 receptor subunit alpha
• IL20RA
• IL-20Ra
• IL-20R-alpha
• interleukin 20 receptor, alpha
• interleukin-20 receptor I
• interleukin-20 receptor subunit alpha
• zcytor7

Background

Official Gene Symbol: IL20RA Gene ID: 53832 (Human) Gene Map Locus: 6q22.33-q23.1 (Human) IL20RA, is a subunit of IL20R, a member of Cytokine Class II receptor super family. It consists of a central transmembrane domain and functionally induces IL20 and IL26 signaling in epithelial cells and keratinocytes. It associates with IL-20RB and forms a functional receptor complex for IL20, IL19, and IL24. It also associates with IL-10RB and forms a unique heterodimeric functional receptor complex for IL-26. Upon ligand binding, it induces signaling through activation of STAT3 and STAT1. IL20RA is specifically expressed in skin suggesting a prominent role in growth and proliferation of keratinocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL20RA