IFN-epsilon Antibody (983338) [Unconjugated]

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IFN-epsilon was detected in immersion fixed paraffin-embedded sections of human endometrial cancer tissue using Mouse Anti-Human IFN-epsilon Monoclonal Antibody (Catalog # MAB9147) at 1 µg/mL for 1 hour at room ...read more

Product Details

Summary
Applications ELISA, IHC
Clone
983338
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

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Catalog# & Formulation Size Price

IFN-epsilon Antibody (983338) [Unconjugated] Summary

Immunogen
E. coli-derived recombinant human IFN-epsilon
Leu22-Arg208
Accession # Q86WN2
Specificity
Detects human IFN-epsilon in direct ELISAs.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry 1-25 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IFN-epsilon Antibody (983338) [Unconjugated]

  • IFNE
  • IFN-E
  • IFNE1PRO655
  • IFNepsilon
  • IFN-epsilon
  • IFNT1
  • Ifn-tau-11
  • INFE1
  • interferon epsilon 1
  • interferon epsilon
  • Interferon epsilon-1
  • interferon tau-1
  • interferon, epsilon
  • interferon-epsilon
  • MGC119018
  • MGC119020

Background

Interferon-epsilon (IFNe) is a type I interferon with expression limited to the brain, lung, intestine and reproductive tract. It has been proposed that unlike other type I interferons, IFNe plays a role in mucosal immunity and protects against pathogens including chlamidia, HIV and herpes simplex virus 2. Its expression is upregulated by TNF alpha. Unlike other type-1 interferons, IFNe is also hormonally regulated, and mouse and human IFNe have been shown to have a binding site in their promoters for progesterone receptor. Epithelial cells isolated from uterine endometrium have higher IFNee expression in the proliferative phase, when estrogen levels are highest. IFNe is the only IFN isoform constituitively expressed in HeLa cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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MAB9147
Applications: ELISA, IHC

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