IFN-epsilon Antibody (983303) [Alexa Fluor® 750]

• Reactivity: Hu
• Applications: ELISA
• Clone: 983303
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

IFN-epsilon Antibody (983303) [Alexa Fluor® 750] Summary

• Immunogen: E. coli-derived recombinant human IFN-epsilon
  Leu22-Arg208
  Accession # Q86WN2
• Specificity: Detects human IFN-epsilon in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IFN-epsilon Antibody (983303) [Alexa Fluor® 750]

• IFNE
• IFN-E
• IFNE1PRO655
• IFNepsilon
• IFN-epsilon
• IFNT1
• Ifn-tau-11
• INFE1
• interferon epsilon 1
• interferon epsilon
• Interferon epsilon-1
• interferon tau-1
• interferon, epsilon
• interferon-epsilon
• MGC119018
• MGC119020

Background

Interferon-epsilon (IFNe) is a type I interferon with expression limited to the brain, lung, intestine and reproductive tract. It has been proposed that unlike other type I interferons, IFNe plays a role in mucosal immunity and protects against pathogens including chlamidia, HIV and herpes simplex virus 2. Its expression is upregulated by TNF alpha. Unlike other type-1 interferons, IFNe is also hormonally regulated, and mouse and human IFNe have been shown to have a binding site in their promoters for progesterone receptor. Epithelial cells isolated from uterine endometrium have higher IFNee expression in the proliferative phase, when estrogen levels are highest. IFNe is the only IFN isoform constituitively expressed in HeLa cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.