Mouse Hyaluronidase 1/HYAL1 ELISA Kit (Colorimetric)

ELISA: Mouse Hyaluronidase 1/HYAL1 ELISA Kit (Colorimetric) [NBP3-11796] - Samples were spiked with high concentrations of Mouse Hyaluronidase 1/HYAL1 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

ELISA: Mouse Hyaluronidase 1/HYAL1 ELISA Kit (Colorimetric) [NBP3-11796] - Standard Curve Reference

• Reactivity: Mu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma and other biological fluids
• Standard Curve Range: 3.91 - 250 ng/mL
• Sensitivity: 2.35 ng/mL

Mouse Hyaluronidase 1/HYAL1 ELISA Kit (Colorimetric) Summary

• Standard Curve Range: 3.91 - 250 ng/mL
• Sensitivity: 2.35 ng/mL
• Assay Type: Sandwich-ELISA
• Inter-Assay: %CV < 6.74
• Intra-Assay: %CV < 6.65
• Spike Recovery: 93 - 110%
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: HYAL1

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Mouse Hyaluronidase 1/HYAL1 ELISA Kit (Colorimetric)

• EC 3.2.1.35
• FUS2
• HYAL1
• HYAL-1
• Hyaluronidase 1
• Hyaluronoglucosaminidase 1
• hyaluronoglucosaminidase-1
• LUCA1
• LuCa-1
• LUCA1hyaluronidase-1
• Lung carcinoma protein 1
• MGC45987
• NAT6
• plasma hyaluronidase
• tumor suppressor LUCA-1

Background

HYAL1 codes for a protein that may have a role in promoting tumor progression and blocking the TGFB1-enhanced cell growth, and is expressed highly in the liver, kidney, and heart, with weaker expression in the lung placenta, and skeletal muscle. There are seven isoforms of HYAL1, with the longest being isoform 1, which is only expressed in bladder and prostate cancer cells and is 435 amino acids long and weighs approximately 48 kDa. Current studies are being done on several diseases and disorders relating to this gene including lung carcinoma, lysosomal storage disease, diabetes mellitus, ovarian cancer, endometrial carcinoma, prostate cancer, and breast cancer. HYAL1 has also been shown to have interactions with GUSB, ARSB, IDUA, FAM107B, and COL2A1 in pathways such as the metabolic, lysosome, and Maroteaux-Lamy syndrome pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: HYAL1