Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Human Pro-MMP-13 DuoSet ELISA, 15 Plate
CLG 3
CLG3EC 3.4.24
collagenase 3
EC 3.4.24.-
EC 3.4.24.22
EC 3.4.24.24
EC 3.4.24.35
EC 3.4.24.65
EC 3.4.24.7
MANDP1
matrix metallopeptidase 13 (collagenase 3)
matrix metalloproteinase 13 (collagenase 3)
Matrix metalloproteinase-13
MMP13
MMP-13
Background
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).