Human IFN-alpha Serum Sample ELISA Kit

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human IFN-alpha Serum Sample ELISA Kit Summary

• Specificity: Human IFN-alpha
• Source: N/A
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: IFNA2

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IFN-alpha Serum Sample ELISA Kit

• IFNA
• IFNA2
• IFNA2b
• IFNalpha
• IFN-alpha
• IFN-alphaA
• INFA2
• interferon alpha 2
• LeIF D

Background

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

Publications for IFN-alpha (41110-1)(4)

Publications using 41110-1

• S Ding, J Diep, N Feng, L Ren, B Li, YS Ooi, X Wang, KF Brulois, LL Yasukawa, X Li, CJ Kuo, DA Solomon, JE Carette, HB Greenberg STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection Nat Commun, 2018-04-16;9(1):1485. 2018-04-16 [PMID: 29662124] (Human)
• Liu L, Cao Z, Chen J Influenza A virus induces interleukin-27 through cyclooxygenase-2 and protein kinase A signaling. J. Biol. Chem., 2012-02-16;287(15):11899-910. 2012-02-16 [PMID: 22343630] (Human)
• Cheng G, Zhao X, Yan W, Wang W, Zuo X, Huang K, Liu Y, Chen J, Wang J, Cong W, Liu M, Gao H, Chen J, Lu Y, Zheng Z Alpha interferon is a powerful adjuvant for a recombinant protein vaccine against foot-and-mouth disease virus in swine, and an effective stimulus of in vivo immune response. Vaccine, 2007-05-24;25(28):5199-208. 2007-05-24 [PMID: 17555848] (Porcine)
• Yoshikawa H, Sato K, Edahiro S, Furukawa Y, Maruta T, Iwasa K, Watanabe H, Takaoka S, Suzuki Y, Takamori M, Yamada M Elevation of IL-12 p40 and its antibody in myasthenia gravis with thymoma. J. Neuroimmunol., 2006-03-29;175(1):169-75. 2006-03-29 [PMID: 16574246] (Human)

Bioinformatics

• Gene Symbol: IFNA2