Human FAP DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human FAP DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: FAP

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human FAP DuoSet ELISA, 15 Plate

• 170 kDa melanoma membrane-bound gelatinase
• DKFZp686G13158
• DPPIV
• EC 3.4.21.-
• FAP
• FAPA
• Fibroblast Activation Protein alpha
• fibroblast activation protein, alpha
• Integral membrane serine protease
• Seprase
• vibronectin

Background

FAP (fibroblast activation protein-alpha; also known as seprase) is a type II transmembrane serine protease that degrades gelatin, Type I collagen, and N-terminal prolines. FAP is induced on reactive stromal fibroblasts in epithelial cancers, sarcomas, and granulation tissue, and may play roles in tumor invasion, tissue remodeling, and wound repair.

Publications for Fibroblast Activation Protein alpha/FAP (DY3715)(10)

Publications using DY3715

• Lee, HJ;Jo, Y;Wei, S;Yu, EH;Lee, S;Ryu, D;Joo, JK; Fibroblast Activation Protein (FAP) as a Serum Biomarker for Fibrotic Ovarian Aging: A Clinical Validation Study Based on Translational Transcriptomic Targets International journal of molecular sciences 2025-08-13 [PMID: 40869127] (Human)
• Z Yuan, H Hu, Y Zhu, W Zhang, Q Fang, T Qiao, T Ma, M Wang, R Huang, Q Tang, F Gao, C Zou, X Gao, G Wang, X Wang Colorectal cancer cell intrinsic fibroblast activation protein alpha binds to Enolase1 and activates NF-&kappaB pathway to promote metastasis Cell Death & Disease, 2021-05-25;12(6):543. 2021-05-25 [PMID: 34035230] (Human)
• B Baráth, R Bogáti, T Miklós, J Kállai, ZA Mezei, Z Bereczky, L Muszbek, É Katona Effect of &alpha2-plasmin inhibitor heterogeneity on the risk of venous thromboembolism Thrombosis Research, 2021-05-11;203(0):110-116. 2021-05-11 [PMID: 33992873] (Human)
• Z Bagoly, B Baráth, R Orbán-Kálm, I Szegedi, R Bogáti, F Sarkady, L Csiba, É Katona Incorporation of &alpha2-Plasmin Inhibitor into Fibrin Clots and Its Association with the Clinical Outcome of Acute Ischemic Stroke Patients Biomolecules, 2021-02-25;11(3):. 2021-02-25 [PMID: 33669007] (Human)
• E Krepela, Z Vanickova, P Hrabal, M Zubal, B Chmielova, E Balaziova, P Vymola, I Matrasova, P Busek, A Sedo Regulation of Fibroblast Activation Protein by Transforming Growth Factor Beta-1 in Glioblastoma Microenvironment International Journal of Molecular Sciences, 2021-01-21;22(3):. 2021-01-21 [PMID: 33494271] (Human)
• JD Solano-Itu, P Errarte, MC Etxezarrag, E Echevarria, J Angulo, JI López, G Larrinaga Altered Tissue and Plasma Levels of Fibroblast Activation Protein-&alpha (FAP) in Renal Tumours Cancers (Basel), 2020-11-16;12(11):. 2020-11-16 [PMID: 33207686] (Human)
• J Liu, Z Zuo, M Zou, T Finkel, S Liu Identification of the transcription factor Miz1 as an essential regulator of diphthamide biosynthesis using a CRISPR-mediated genome-wide screen PLoS Genet, 2020-10-15;16(10):e1009068. 2020-10-15 [PMID: 33057331] (Human)
• TW Bainbridge, DR Dunshee, NM Kljavin, NJ Skelton, J Sonoda, JA Ernst Selective Homogeneous Assay for Circulating Endopeptidase Fibroblast Activation Protein (FAP) Sci Rep, 2017-10-02;7(1):12524. 2017-10-02 [PMID: 28970566] (Human)
• S Uitte de W, FM Keane, DG Bowen, JJMC Malfliet, HE Zhang, B Maneck, GW McCaughan, FWG Leebeek, DC Rijken, MD Gorrell Circulating fibroblast activation protein activity and antigen levels correlate strongly when measured in liver disease and coronary heart disease PLoS ONE, 2017-06-05;12(6):e0178987. 2017-06-05 [PMID: 28582421] (Human)
• Matrasova I, Busek P, Balaziova E, Sedo A Heterogeneity of molecular forms of dipeptidyl peptidase-IV and fibroblast activation protein in human glioblastomas. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, 2017-04-26;161(3):252-260. 2017-04-26 [PMID: 28452380] (Human)

Bioinformatics

• Gene Symbol: FAP