HspBP1 Overexpression Lysate (Denatured)

Product Discontinued

HspBP1 Overexpression Lysate (Denatured) Summary

• Description: Quality control test: Transient overexpression cell lysate was tested with Anti-HSPBP1 antibody by Western Blots. Plasmid: pCMV-HSPBP1 full-length
• Gene: HSPBP1

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for Array

• Type: Overexpression
• Protein State: Denatured

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for HspBP1 Overexpression Lysate (Denatured)

• FES1
• Heat shock protein-binding protein 1
• Hsp70 binding protein 1
• hsp70 interacting protein
• hsp70-binding protein 1
• Hsp70-binding protein 2
• Hsp70-interacting protein 1
• Hsp70-interacting protein 2
• HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
• HSPBP
• HspBP1
• hspBP2

Background

Heat shock protein binding protein is an Hsp70-interacting protein that was first isolated from a human heart cDNA library using the yeast two-hybrid system. HspBP1 binds the ATPase domain of Hsp70, and inhibits Hsp70 chaperone activity. More recently HspBP1 was found to promote nucleotide dissociation from Hsc70 and is capable of altering the confirmation of the Hsp70 ATPase domain. HspBP1 is capable of regulating any Hsp70 activity that requires ATPase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: HSPBP1