Hsp70 interacting protein HIP Antibody (CL3708) - BSA Free

Western Blot: Hsp70 interacting protein HIP Antibody (CL3708) [NBP2-61615] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10Lane 2: Human cell line RT-4

Immunohistochemistry-Paraffin: Hsp70 interacting protein HIP Antibody (CL3708) [NBP2-61615] - Staining of human prostate cancer shows moderate cytoplasmic positivity in tumor cells.

Immunohistochemistry: Hsp70 interacting protein HIP Antibody (CL3708) [NBP2-61615] - Staining of human colorectal cancer shows cytoplasmic immunoreactivity in tumor cells.

Immunohistochemistry: Hsp70 interacting protein HIP Antibody (CL3708) [NBP2-61615] - Staining of human kidney shows cytoplasmic positivity in renal tubules and glomerulus cells.

Immunohistochemistry: Hsp70 interacting protein HIP Antibody (CL3708) [NBP2-61615] - Staining of human fallopian tube shows strong cytoplasmic immunoreactivity in epithelial cells.

Immunohistochemistry: Hsp70 interacting protein HIP Antibody (CL3708) [NBP2-61615] - Staining of human endometrium shows cytoplasmic immunoreactivity in glandular epithelium cells.

Immunohistochemistry-Paraffin: Hsp70 interacting protein HIP Antibody (CL3708) [NBP2-61615] - Staining of human liver shows cytoplasmic positivity in hepatocytes.

Immunohistochemistry-Paraffin: Hsp70 interacting protein HIP Antibody (CL3708) [NBP2-61615] - Staining of human breast cancer shows cytoplasmic immunoreactivity in tumor cells.

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: CL3708
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

Hsp70 interacting protein HIP Antibody (CL3708) - BSA Free Summary

• Description: Novus Biologicals Mouse Hsp70 interacting protein HIP Antibody (CL3708) - BSA Free (NBP2-61615) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed using a recombinant protein derived from P50502, with the exact immunogen sequence remaining proprietary.
• Predicted Species: Mouse (96%), Rat (93%). Backed by our 100% Guarantee.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ST13
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10000 - 1:20000
  • Immunohistochemistry-Paraffin 1:10000 - 1:20000
  • Western Blot 1 ug/ml
• Application Notes: IHC-Paraffin HIER pH6 retrieval is recommended.
• Control Peptide:

  Hsp70 interacting protein HIP Recombinant Protein Antigen (NBP2-61615PEP)

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Protein A purified

Alternate Names for Hsp70 interacting protein HIP Antibody (CL3708) - BSA Free

• AAG2
• aging-associated protein 2
• FAM10A1FAM10A4
• heat shock 70kD protein binding protein
• Hip
• HIPFLJ27260
• HOP
• hsc70-interacting protein
• Hsp70-interacting protein
• HSPABP1
• P48MGC129952
• PRO0786
• Progesterone receptor-associated p48 protein
• Protein FAM10A1
• Putative tumor suppressor ST13
• Renal carcinoma antigen NY-REN-33
• SNC6HSPABP
• suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
• suppression of tumorigenicity 13 (colon carcinoma) (Hsp70-interacting protein)
• Suppression of tumorigenicity 13 protein

Background

Hsp70 interacting protein HIP is encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that is a candidate tumor suppressor gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ST13