HOXB7 Antibody (864614) [Alexa Fluor® 647]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 864614
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

HOXB7 Antibody (864614) [Alexa Fluor® 647] Summary

• Immunogen: E. coli-derived recombinant human HOXB7
  Met1-Asn123
  Accession # P09629
• Specificity: Detects human HOXB7 in ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for HOXB7 Antibody (864614) [Alexa Fluor® 647]

• HHO.C1
• homeo box 2C
• homeo box B7
• homeo box c1 protein
• homeobox B7
• Homeobox protein HHO.C1
• Homeobox protein Hox-2C
• homeobox protein Hox-B7
• HOX2
• Hox-2.3
• HOX2C
• HOX2CHox-2.3
• HOXB7

Background

HOXB7 (Homeobox protein B7), also called Hox-2C, is a 24 kDa (predicted) member of the Antp homeobox family of transcription factors. It is widely expressed and is overexpressed in many cancers such as melanoma and tumors in lung and breast. It promotes tumorigenesis by promoting activities such as proliferation, invasion, epithelial-mesenchymal transition and angiogenesis.  Human HOXB7 is a 217 amino acid (aa) protein with an Antp-type hexapeptide (aa 126-131) that mediates heterodimerization, and a DNA-binding homeobox domain (aa 137-196). Human HOXB7 aa 1-123 shares 92% aa sequence identity with mouse and rat HOXB7.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.