HOXB1 Antibody [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: ICC/IF
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Alexa Fluor 488

HOXB1 Antibody [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human HOXB1
  Met1-Thr192
  Accession # P14653
• Specificity: Detects human HOXB1 in direct ELISAs. In direct ELISAs, less than 2% cross-reactivity with recombinant human (rh) HOXA1, rhHOXB4, and rhHOXA9 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for HOXB1 Antibody [Alexa Fluor® 488]

• homeo box 2I
• homeo box B1
• homeobox B1
• Homeobox protein Hox-2I
• homeobox protein Hox-B1
• HOX2
• Hox-2.9
• HOX2I
• HOX2IMGC116844
• HOXB1
• MGC116843
• MGC116845

Background

HOXB1 (Homeobox protein B1; also HOX-2I) is a 32 kDa (predicted) member of the Antp homeobox family, labial subfamily of transcription factors. It is expressed in rhombomere-4 (r-4) of the hindbrain, where it drives the development of r-4 derived structures. Among these are the motor neurons of the facial nerve, and neural crest cells that form Schwann cells plus cartilage and bone of the neck and ear. Human HOXB1 is 301 amino acids (aa) in length. It contains an Antp-type hexapeptide (aa 179-184) that mediates heterodimerization, and a DNA-binding homeobox domain (aa 203-262). There is one potential splice variant that shows a 40 aa substitution for aa 193-301. Over aa 1-192, human HOXB1 shares 82% aa identity with mouse HOXB1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.