HLA DPB1 Antibody (6C6)

Images

 
Western Blot: HLA DPB1 Antibody (6C6) [H00003115-M01] - Analysis of HLA-DPB1 expression in transfected 293T cell line by HLA-DPB1 monoclonal antibody (M01), clone 6C6.Lane 1: HLA-DPB1 transfected lysate(29 KDa).Lane 2: ...read more
Immunohistochemistry-Paraffin: HLA DPB1 Antibody (6C6) [H00003115-M01] - Analysis of monoclonal antibody to HLA-DPB1 on formalin-fixed paraffin-embedded human lymph node. Antibody concentration 0.5 ug/ml.
Immunoprecipitation: HLA DPB1 Antibody (6C6) [H00003115-M01] - Analysis of HLA-DPB1 transfected lysate using anti-HLA-DPB1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with HLA-DPB1 monoclonal ...read more
Sandwich ELISA: HLA DPB1 Antibody (6C6) [H00003115-M01] - Detection limit for recombinant GST tagged HLA-DPB1 is 10 ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC-P, IP
Clone
6C6
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

HLA DPB1 Antibody (6C6) Summary

Immunogen
HLA-DPB1 (AAH13184, 1 a.a. - 258 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYVYQGRQECYAFNGTQRFLERYIYNREEYARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRVCRHNYELDEAVTLQRRVQPKVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYICQVEHTSLDSPVTVEWKAQSDSAQSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRGSA
Specificity
HLA-DPB1 - major histocompatibility complex, class II, DP beta 1
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
HLA-DPB1
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
Application Notes
Antibody reactivity against transfected lysate and recombinant protein for WB. It has been used for IHC-P and ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for HLA DPB1 Antibody (6C6)

  • DP beta 1 chain
  • DPB1
  • HLA class II histocompatibility antigen, DP(W4) beta chain
  • HLA DP14-beta chain
  • HLA-DP histocompatibility type, beta-1 subunit
  • HLA-DP1B
  • HLA-DPB
  • major histocompatibility complex class II HLA DPB1 protein
  • major histocompatibility complex, class II, DP beta 1
  • MHC class II antigen beta chain
  • MHC class II antigen DP beta 1 chain
  • MHC class II antigen DPB1
  • MHC class II antigen DPbeta1
  • MHC class II HLA-DP-beta
  • MHC HLA DPB1

Background

HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol HLA-DPB1
Entrez
OMIM
Uniprot