HLA DPB1 Products

Antibodies
Lysates
HLA DPB1 Overexpression Lysat ...
HLA DPB1 Overexpression Lysate
NBL1-11583
Species: Hu
Applications: WB
Proteins
Recombinant Human HLA DPB1 GS ...
Recombinant Human HLA DPB1 GST (N-...
H00003115-P01
Species: Hu
Applications: WB, ELISA, PA, AP
Recombinant Human HLA DPB1 GS ...
Recombinant Human HLA DPB1 GST (N-...
H00003115-P02
Species: Hu
Applications: WB, ELISA, PA, AP
HLA DPB1 Recombinant Protein ...
HLA DPB1 Recombinant Protein Antigen
NBP2-56722PEP
Species: Hu
Applications: AC

Description

HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 3115
Alternate Names
  • DP beta 1 chain
  • DPB1
  • HLA class II histocompatibility antigen, DP(W4) beta chain
  • HLA DP14-beta chain
  • HLA-DP histocompatibility type, beta-1 subunit
  • HLA-DP1B
  • HLA-DPB
  • major histocompatibility complex class II HLA DPB1 protein
  • major histocompatibility complex, class II, DP beta 1
  • MHC class II antigen beta chain
  • MHC class II antigen DP beta 1 chain
  • MHC class II antigen DPB1
  • MHC class II antigen DPbeta1
  • MHC class II HLA-DP-beta
  • MHC HLA DPB1

Research Areas for HLA DPB1

Find related products by research area and learn more about each of the different research areas below.

Asthma
Diabetes Research
Immunology

PTMs for HLA DPB1

Learn more about PTMs related to HLA DPB1.

Carboxylation
Citrullination

Bioinformatics Tool for HLA DPB1

Discover related pathways, diseases and genes to HLA DPB1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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Related HLA DPB1 Blog Posts

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