HLA DOA Antibody

Product Discontinued

HLA DOA Antibody Summary

• Immunogen: HLA-DOA (NP_002110, 1 a.a. ~ 250 a.a) full-length human protein.MALRAGLVLGFHTLMTLLSPQEAGATKADHMGSYGPAFYQSYGASGQFTHEFDEEQLFSVDLKKSEAVWRLPEFGDFARFDPQGGLAGIAAIKAHLDILVERSNRSRAINVPPRVTVLPKSRVELGQPNILICIVDNIFPPVINITWLRNGQTVTEGVAQTSFYSQPDHLFRKFHYLPFVPSAEDVYDCQVEHWGLDAPLLRHWELQVPIPPPDAMETLVCALGLAIGLVGFLVGTVLIIMGTYVSSVPR
• Specificity: HLA-DOA - major histocompatibility complex, class II, DO alpha,
• Clonality: Polyclonal
• Host: Mouse
• Gene: HLA-DOA
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: This is unpurified antiserum so it is not possible to supply the specific antibody concentration.
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for HLA DOA Antibody

• HLA class II histocompatibility antigen, DO alpha chain
• HLA-D0-alpha
• HLA-DNAHLADZ
• HLA-DZA
• lymphocyte antigen
• major histocompatibility complex, class II, DN alpha
• major histocompatibility complex, class II, DO alpha
• MHC class II antigen DOA
• MHC DN-alpha
• MHC DZ alpha

Background

HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HLA-DOA
• Uniprot:
  • NP_002110(Human)