HIPK1 Antibody [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 488

HIPK1 Antibody [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human HIPK1
  Gln701-Ser900
  Accession # Q86Z02
• Specificity: Detects endogenous human HIPK1 in Western blots. Approximately 15% cross reactivity to HIPK2 is observed in Western blot.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for HIPK1 Antibody [Alexa Fluor® 488]

• EC 2.7.11.1
• HIPK1
• homeodomain interacting protein kinase 1
• homeodomain interacting protein kinase 1-like protein
• homeodomain-interacting protein kinase 1
• KIAA0630MGC26642
• MGC33446
• MGC33548
• Myak
• Nbak2
• nuclear body associated kinase 2b

Background

HIPK1 (Homeodomain-interacting protein kinase 1) is a 120‑130 kDa member of the HIPK subfamily, CMGC Ser/Thr family of protein kinases. It is ubiquitously expressed, and plays a role in transcriptional regulation and signal transduction. Human HIPK1 is 1210 amino acids (aa) in length. It contains a protein kinase domain (aa 190‑518) that phosphorylates itself as well as Daxx and p53, an interaction region between aa 581‑847, a PEST sequence (aa 889‑973) and a YH domain (aa 1066‑1209) that recruits CtBP. Four different splice variants have been identified. Over aa 701‑900, human and mouse HIPK1 share 97% aa identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.