HHEX Antibody (2018B) [Alexa Fluor® 647]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications Flow
Clone
2018B
Clonality
Monoclonal
Host
Rabbit
Conjugate
Alexa Fluor 647

HHEX Antibody (2018B) [Alexa Fluor® 647] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
E. coli-derived recombinant human HHEX
Thr111-Gly270
Accession # Q6UX06
Specificity
Detects human HHEX in direct ELISAs and Western blots.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for HHEX Antibody (2018B) [Alexa Fluor® 647]

  • hematopoietically expressed homeobox
  • Hex
  • HEXHMPH
  • HHEX
  • HMPH
  • Homeobox protein HEX
  • Homeobox protein PRH
  • HOX11L-PEN
  • PRH
  • PRHhematopoietically-expressed homeobox protein HHEX
  • PRHX
  • PRHXhomeobox, hematopoietically expressed
  • proline-rich homeodomain-containing transcription factor

Background

Hematopoietically-expressed homeobox protein (HHEX), also known as HEX, PRH and PRHX, is a 35-40 kDa member of the Homeobox family of transcription factors.  Family members are distinguished by an evolutionarily conserved DNA-binding homeodomain of 60 amino acids (aa), which for HHEX spans aa 137-196.  Human HHEX was initially isolated from hematopoietic tissue, and is present in several hematopoietic progenitors, where its expression is down-regulated during terminal cell differentiation.  HHEX is also expressed in the anterior visceral endoderm during early mouse development, and in some adult tissues of endodermal origin, including liver, lung and thyroid.  HHEX knockout in mice is embryonic lethal, with impaired forebrain, liver and thyroid development.  Human HHEX is 270 aa in length, and over aa 111-270, shares 93% and 95% identity with mouse and rat HHEX, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Entrez
Uniprot