HCN3 Antibody (TLL6C5)

Immunohistochemistry-Paraffin: HCN3 Antibody (TLL6C5) [NB100-74438] - Both normal and cancer biopsies of deparaffinized Human brain tissues.

Immunohistochemistry-Paraffin: HCN3 Antibody (TLL6C5) [NB100-74438] - Both normal and cancer biopsies of deparaffinized Human colon carcinoma tissues.

Product Discontinued

HCN3 Antibody (TLL6C5) Summary

• Immunogen: Synthetic peptide corresponding to residues T(640) L L A R S A R R S A G S P A S P L V P V R A G P L L A R G P W A S T S(675) of rat HCN3.
• Specificity: HCN3 (TLL6C5)
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Rat
• Gene: HCN3
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:1000
  • Immunohistochemistry-Paraffin 1:10 - 1:500
  • Western Blot 1:5000
• Application Notes: WB: Detects an approx. 90 KDa protein representing HCN3.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Ascites
• Preservative: 0.05% Sodium Azide
• Purity: Unpurified

Alternate Names for HCN3 Antibody (TLL6C5)

• HCN3
• hyperpolarization activated cyclic nucleotide-gated potassium channel 3
• KIAA1535
• KIAA1535MGC131493
• potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3

Background

HCN3 is a member of the family of hyperpolarization-activated and cyclic-nucleotide-gated (HCN) channels. HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity. HCN3 has been detected in the brain, but with less expression than other HCN channels.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HCN3
• Entrez:
  • 57657(Human)
  • 15168(Mouse)
  • 114245(Rat)