HCAP-G Antibody (4B1)

Product Discontinued

HCAP-G Antibody (4B1) Summary

• Immunogen: HCAP-G (AAH00827, 336 a.a. ~ 435 a.a) partial recombinant protein with GST tag.TTFQNEDEKNKEVYMTPLRGVKATQASKSTQLKTNRGQRKVTVSARTNRRCQTAEADSESDHEVPEPESEMKMRLPRRAKTAALEKSKLNLAQFLNEDLS
• Specificity: HCAP-G - chromosome condensation protein G
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: NCAPG
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1:500
• Application Notes: Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunohistochemistry (paraffin) and ELISA.

Reactivity Notes

Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for HCAP-G Antibody (4B1)

• CAP-G
• CAPGHCAP-G
• CHCG
• chromosome condensation protein G
• Chromosome-associated protein G
• condensin complex subunit 3
• Condensin subunit CAP-G
• FLJ12450
• hCAP-G
• Melanoma antigen NY-MEL-3
• MGC126525
• Non-SMC condensin I complex subunit G
• non-SMC condensin I complex, subunit G
• NYMEL3
• NY-MEL-3
• XCAP-G homolog

Background

Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin intomitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA inthe presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type IItopoisomerases

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for HCAP-G Antibody (H00064151-M01)(2)

Publications using H00064151-M01

• Yokoyama Y, Zhu H, Zhang R, Noma K A novel role for the condensin II complex in cellular senescence. Cell Cycle 2015-01-01 [PMID: 26017022] (WB)
• Satow R, Shitashige M, Kanai Y et al. Combined functional genome survey of therapeutic targets for hepatocellular carcinoma. Clin Cancer Res 16(9):2518-28. 2010-05-01 [PMID: 20388846]

Bioinformatics

• Gene Symbol: NCAPG
• Entrez:
  • 64151(Human)
• OMIM:
  • 606280(Human)
• Uniprot:
  • AAH00827(Human)